Bioactive Glass and Platelet Rich Fibrin in Intrabony Defects
Status:
Completed
Trial end date:
2016-08-01
Target enrollment:
Participant gender:
Summary
Background: Platelet-rich fibrin (PRF) and bioactive glass putty has been shown to be
effective in promoting reduction in probing depth, gain in clinical attachment, and defect
fill in intrabony periodontal defects. The individual role played by bioactive glass putty in
combination with PRF is yet to be elucidated.
AIM: To compare the clinical effectiveness of the combination of Plaltelet Rich Fibrin and
Bioactive Glass Putty and Bioactive glass putty regenerative techniques for intrabony defects
in humans.
Material and methods: Ten pairs of intrabony defects were surgically treated with PRF and
Bioactive glass putty (Test group) on one side or bioactive glass putty (Control group) on
other side. The primary outcomes of the study included changes in probing depth, attachment
level and bone fill of Osseous defect. The clinical parameters were recorded at baseline, 3,
6, and 9 months. Radiographic assessment was done using standardized intra oral periapical
radiographs. Comparisions were made within each group between baseline, 3 months, 6 months
and 9 months using the ANOVA test followed by Bonferroni test.