Overview

Binimetinib and Encorafenib for the Treatment of Pancreatic Cancer in Patients With a Somatic BRAF V600E Mutation

Status:
Recruiting
Trial end date:
2024-12-29
Target enrollment:
Participant gender:
Summary
This phase II trial studies the side effects and how well the combination of binimetinib and encorafenib work in treating patients with pancreatic cancer with a somatic BRAF V600E mutation. Binimetinib and encorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving binimetinib and encorafenib may work better compared to the usual treatment in treating patients with pancreatic cancer and a somatic BRAF V600E mutation.
Phase:
Phase 2
Details
Lead Sponsor:
Academic and Community Cancer Research United
Collaborator:
National Cancer Institute (NCI)