Biliary Atresia, Hepatic Buffer Response and Sevoflurane
Status:
Completed
Trial end date:
2014-02-01
Target enrollment:
Participant gender:
Summary
To evaluate the effects of sevoflurane on hepatic blood flow (HBF) and hepatic arterial
buffer response (HABR) in infants with obstructive jaundice by Doppler ultrasound.Twenty-five
infants with biliary atresia (1-3 months-of-age) scheduled for a Kasai procedure were
enrolled. portal vein blood flow (PBF), hepatic arterial blood flow (HABF) and hepatic blood
flow (HBF) were measured by Doppler ultrasound before induction, and after inhalation of 2
and 3% sevoflurane.