Bilateral Subthalamic Stimulation in PD Patients With Impulse Control Disorders - STIMPulseControl
Status:
RECRUITING
Trial end date:
2028-07-15
Target enrollment:
Participant gender:
Summary
The focus of the study is on patients Parkinson's disease showing as well behavioral disorders that can be described as pathological and are summarized under the term impulse control disorder (ICD). Changes in behavior and also pathological disorders are a common side effect of treatment for Parkinson's disease. The goal of this academic study is to compare the effect of surgical (deep brain stimulation, DBS) treatment combined with a coordinated and adapted best medical treatment (BMT) to be compared with the effect of optimized best medical treatment (BMT) alone. The stimulation arm (DBS+BMT) as well as the medication arm (BMT only) will be monitored according to clinical routine. Participants will have to agree to be randomly assigned to either deep brain stimulation in combination with the best medical treatment (DBS group) or the best medical treatment alone (BMT group). Participants will have to come regularly according to clinical routine to the clinic and complete various questionaires and scales for the study.
Phase:
NA
Details
Lead Sponsor:
University of Kiel
Collaborators:
Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC) Czech Technical University in Prague Insel Gruppe AG, University Hospital Bern Philipps University Marburg University Hospital Schleswig-Holstein University of Pennsylvania