Overview

Bevacizumab With or Without Sunitinib in Sunitinib-Refractory Renal Cell Carcinoma

Status:
Withdrawn
Trial end date:
2009-09-01
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to further define an effective strategy for people with renal cell carcinoma and to learn the safety and effectiveness of two different types of sunitinib-refractory treatments: Bevacizumab alone or a combination of sunitinib and bevacizumab. Sunitinib is an FDA approved drug and is currently one of the standard treatments for advanced renal cell carcinoma. However, some people who receive this treatment do not respond to treatment or they stop responding to treatment. Bevacizumab is an FDA approved drug used for the treatment of several cancers however, is not yet approved for use in renal cell carcinoma.
Phase:
Phase 2
Details
Lead Sponsor:
Massachusetts General Hospital
Collaborators:
Beth Israel Deaconess Medical Center
Pfizer
Treatments:
Bevacizumab
Sunitinib