Bevacizumab, Erlotinib and 5-Fluorouracil With External Beam Radiation Therapy in Locally Advanced Rectal Cancer
Status:
Completed
Trial end date:
2011-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is determine the safety of 5-fluorouracil, bevacizumab and
erlotinib when administered in combination with external beam radiation therapy(Phase I
portion) as well as to begin to collect information about whether this combination treatment
is effective in treating(Phase II portion) patients with locally advanced rectal cancer.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Massachusetts General Hospital
Collaborators:
Beth Israel Deaconess Medical Center Dana-Farber Cancer Institute Genentech, Inc.