Overview

Best Treatment Choice for Osteonecrosis of the Jaw

Status:
Not yet recruiting
Trial end date:
2024-01-01
Target enrollment:
Participant gender:
Summary
BETCON is a pragmatic randomized controlled open-label multi-center study in patients with newly diagnosed stage I-II MRONJ designed to answer the question whether minimally invasive management with LPRF membranes or primary surgical treatment is better than the standard of care of conservative therapy alone. The primary end-point is the time to mucosal healing. Secondary end-points consist of supporting measures of efficacy, patient reported symptoms, quality of life, well-being, and functioning.
Phase:
Phase 4
Details
Lead Sponsor:
Tim Van den Wyngaert
Collaborators:
Kom Op Tegen Kanker
Kom op tegen Kanker (Stand up to Cancer)
Treatments:
Amoxicillin
Anti-Bacterial Agents
Chlorhexidine
Chlorhexidine gluconate