Benefit of a Single Preoperative Dose of Antibiotics for the Prevention of Surgical Site Infections
Status:
Completed
Trial end date:
2005-03-01
Target enrollment:
Participant gender:
Summary
In a rural hospital in Tanzania the rate of surgical site infections (SSI) was 21.6%.
Inappropriate choice of antibiotics and of administration time were determined as sole risk
factors in this setting. After implementation of a standardized procedure with a single shot
dose of Amoxicillin/Clavulanic Acid approximately 30 min. preoperatively the rate of SSI
dropped by 80% in spite of procedural risk factors like poor hygiene etc.