Basilar Artery Occlusion Chinese Endovascular Trial
Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
Endovascular treatment of acute ischemic stroke has shown strong benefit in several
prospective randomized trials in the anterior circulation and endovascular therapy for
basilar artery occlusion has shown promising results in several single-arm studies. This has
led to a broad adoption of these techniques which are now considered standard of care in many
institutions despite the lack of adequate evidence to prove their benefit. Indeed, the rates
of symptomatic intracerebral hemorrhage in these studies have consistently been around 5%
which raises the question as to whether patients could actually be harmed as opposed to
helped by these procedures. This is a prospective, multi-center, randomized, controlled,
open, blinded-endpoint trial, with the aim to evaluate the hypothesis that mechanical
embolectomy with the Solitaire device is superior to medical management alone in achieving
better outcomes in subjects presenting with an acute ischemic stroke caused by occlusion of
the basilar artery within 6-24 hours from symptom onset.
Phase:
N/A
Details
Lead Sponsor:
Xuanwu Hospital, Beijing
Collaborators:
Baotou Central Hospital Beijing Luhe Hospital Beijing Tiantan Hospital Changhai Hospital Chongqing Three Gorges Central Hospital First Hospital of Jilin University Hebei General Hospital Henan Provincial Hospital Henan Provincial People's Hospital Liaocheng People's Hospital Liaocheng Third People's Hospital Linyi People's Hospital Luoyang Central Hospital Nanjing First People's Hospital Nanning Second People's Hospital Nantong University Nanyang Central Hospital Peking University Binhai Hospital PLA 148 Hospital, Zibo, Shandong PLA 264 Hospital, Taiyuan, Shanxi Second Affiliated Hospital of Soochow University Shengli Oilfield Hospital Shenzhen Bao'an District People's Hospital Subei People's Hospital of Jiangsu Province The 101st Hospital of Chinese People's Liberation Army The 306 Hospital of People's Liberation Army The 904 Hospital of PLA The 985 Hospital of PLA, Taiyuan, Shanxi The Affiliated Hospital Of Guizhou Medical University The Affiliated Hospital of Northwest University, Xi'an NO.3 Hospital The Fifth Central Hospital of Tianjin，TianJin The First Affiliated Hospital of Dalian Medical University The First Affiliated Hospital of Shanxi Medical University The First Affiliated Hospital with Nanjing Medical University The First Hospital of Jilin University The First People's Hospital of Changzhou The Military General Hospital of Beijing, PLA The Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine Tianjin Huanhu Hospital Tianjin TEDA Hospital Xinqiao Hospital of Chongqing Yantaishan Hospital Zhangzhou Municipal Hospital of Fujian Province Zhongshan People's Hospital, Guangdong, China