Overview

Baricitinib in CPPD - the BAPTIST Study

Status:
NOT_YET_RECRUITING
Trial end date:
2027-01-01
Target enrollment:
Participant gender:
Summary
The aim of this clinical trial is to determine if baricitinib is effective in treating calcium pyrophosphate deposition disease (CPPD) in adults. The primary objective is to assess its impact on joint inflammation. The key questions the study seeks to answer are: * Can baricitinib reduce inflammation in affected joints? * Will baricitinib lead to changes in ultrasound findings, such as calcium crystal deposition and synovitis? Researchers will compare baricitinib to other treatments, including methylprednisolone, colchicine, hydroxychloroquine, and methotrexate with folic acid, for managing CPPD.
Phase:
PHASE2
Details
Lead Sponsor:
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Treatments:
Adrenal Cortex Hormones
baricitinib
Colchicine
Folic Acid
Hydroxychloroquine
Methotrexate
Methylprednisolone