Bacterial Contamination: Iodine vs Saline Irrigation in Pediatric Spine Surgery

• Status: Completed
• Trial end date: 2019-07-12
• Target enrollment: 0
• Participant gender: All

Summary

This study will evaluate the safety of povidone-iodine irrigation in pediatric spinal patients by collecting pre- and post-operative safety labwork. Furthermore, the efficacy of povidone-iodine and normal saline irrigation at reducing bacterial contamination of the surgical wound will be measured by collecting cultures before and after irrigation.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Boston Children's Hospital; Boston Children’s Hospital
• Treatments: Cadexomer iodine; Iodine; Povidone; Povidone-Iodine

Criteria

Inclusion Criteria:

1. Age 3 to 18 years on day of surgery

2. diagnosis of spinal deformity

3. undergoing elective posterior spine multi-level instrumentation surgery

Exclusion Criteria:

1. Documented renal failure

2. documented allergy to iodine or shellfish

3. previous spine fusion surgery

4. undergoing elective posterior spine single-level instrumentation surgery

5. undergoing anterior spine multi-level instrumentation surgery

6. current antibiotic use.