Bacteria Entering the Blood Stream From Tooth Extractions and Tooth Brushing
Status:
Completed
Trial end date:
2006-06-01
Target enrollment:
Participant gender:
Summary
The major purposes of this prospective, randomized, clinical study are to:
1. Determine and compare the true incidence, nature, magnitude, and duration (INMD) of
bacteremia (bacteria found in the bloodstream) resulting from a highly invasive dental
office procedure (tooth extraction) and a minimally invasive and naturally occurring
source of bacteremia (tooth brushing);
2. Measure the effect of the American Heart Association's guidelines for amoxicillin
prophylaxis (preventive treatment) on the INMD of bacteremia resulting from a single
tooth extraction.
Phase:
Phase 2
Details
Lead Sponsor:
Atrium Health Carolinas Healthcare System
Collaborator:
National Institute of Dental and Craniofacial Research (NIDCR)