Periodic ventilation that includes CHEYNE Stokes ventilation is a pathological pattern
characterized by alternating periods of hyperpneas and apnea-hypopneas. It occurs generally
during sleep, at high altitude and in hypoxic conditions in healthy subjects, and in some
diseases like congestive heart failure. One study conducted on an animal model suggested that
baclofen, a drug already used against spasticity in humans, could also be effective against
periodic ventilation. The goal of the study is therefore to assess this hypothesis on
hypoxia-induced periodic ventilation in healthy subjects during sleep.