Overview BYL719 and Nab-Paclitaxel in Locally Recurrent or Metastatic HER-2 Negative Breast Cancer Status: Active, not recruiting Trial end date: 2022-03-01 Target enrollment: Participant gender: Summary Investigate the use of BYL719 (alpelisib) as combination therapy with Nab-Paclitaxel in locally recurrent or metastatic HER-2 negative breast cancer. Phase: Phase 1/Phase 2 Details Lead Sponsor: Priyanka SharmaUniversity of Kansas Medical CenterCollaborator: Novartis PharmaceuticalsTreatments: Albumin-Bound PaclitaxelPaclitaxelTaxane