Overview

BV-AVD-R Treatment Children Hodgkin's Lymphoma

Status:
ENROLLING_BY_INVITATION
Trial end date:
2025-12-31
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to use modified Brentuximab Vedotin+doxorubicin+vinblastine+dacarbazine+Rituximab(BV-AVD-R) regimen in Chinese Classical Hodgkin's Lymphoma(HL) children. The main questions it aims to answer are: * \[Overall Response Rate(ORR) :Complete Response(CR)+Partial Response(PR)\] * \[progression-free survival (PFS), event-free survival (EFS) and overall survival (OS) at 6 months and 1 year.\] Participants will be given modified BV-AVD-R regimen according to rapid early responders (RER) or slow early responders (SER) after 2 cycles.
Phase:
PHASE2
Details
Lead Sponsor:
Beijing Children's Hospital
Treatments:
Brentuximab Vedotin
Dacarbazine
Doxorubicin
liposomal doxorubicin
Rituximab
Vincristine