Overview

BPM31510 in Treating Patients With Recurrent High-Grade Glioma Previously Treated With Bevacizumab

Status:
Completed
Trial end date:
2021-06-26
Target enrollment:
Participant gender:
Summary
This phase I trial studies the side effects and best dose of ubidecarenone injectable nanosuspension (BPM31510) in treating patients with high-grade glioma (anaplastic astrocytoma or glioblastoma) that has come back and have been previously treated with bevacizumab. BPM31510 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Phase:
Phase 1
Details
Lead Sponsor:
Seema Nagpal
Collaborator:
National Cancer Institute (NCI)
Treatments:
Bevacizumab
Coenzyme Q10
Ubiquinone