Overview

BOAT: Beta Blocker Uptitration With OptiVol After Cardiac Resynchronization Therapy (CRT)

Status:
Terminated
Trial end date:
2009-05-01
Target enrollment:
Participant gender:
Summary
Many heart failure patients are unable to reach target beta blocker doses. This study will address whether cardiac resynchronization therapy (CRT) will enable uptitration of beta-blockers to target doses and whether it will favorably affect remodeling by reducing left ventricular end systolic volume (LVESV), with measurable clinical benefit, beyond CRT alone (without changes in beta-blocker dose).
Phase:
Phase 4
Details
Lead Sponsor:
St. Luke's-Roosevelt Hospital Center
Collaborator:
Medtronic
Treatments:
Adrenergic beta-Antagonists
Carvedilol
Metoprolol