Overview

BIVV020 in Prevention and Treatment of Antibody-mediated Rejection (AMR)

Status:
Not yet recruiting
Trial end date:
2025-04-09
Target enrollment:
Participant gender:
Summary
Primary Objectives: - Cohort A: To evaluate the efficacy of BIVV020 in prevention of AMR - Cohort B: To evaluate the efficacy of BIVV020 in treatment of active AMR Secondary Objectives: - To assess the overall efficacy of BIVV020 in prevention or treatment of AMR - To characterize the safety and tolerability of BIVV020 in kidney transplant participants - To characterize the pharmacokinetic (PK) profile of BIVV020 in kidney transplant participants - To evaluate the immunogenicity of BIVV020
Phase:
Phase 2
Details
Lead Sponsor:
Sanofi
Treatments:
Antibodies
Antilymphocyte Serum
gamma-Globulins
Immunoglobulins
Immunoglobulins, Intravenous
Rho(D) Immune Globulin
Rituximab
Tacrolimus