Overview

BIBF 1120 for Recurrent High-Grade Gliomas

Status:
Completed
Trial end date:
2014-07-01
Target enrollment:
Participant gender:
Summary
BIBF 1120 is a newly discovered compound that may stop cancer cells from growing abnormally. This drug is currently being used in treatment for other cancers in research studies and information from those other research studies suggests that this agent, BIBF 1120, may help to stop recurrent malignant glioma cells from multiplying and it may also prevent the growth of new blood vessels at the site of the tumor. In this research study, the investigators are looking to see how well BIBF 1120 works in patients with recurrent malignant gliomas.
Phase:
Phase 2
Details
Lead Sponsor:
Patrick Y. Wen, MD
Collaborators:
Boehringer Ingelheim
Massachusetts General Hospital
The Cleveland Clinic
University of Virginia
Wake Forest Baptist Health
Wake Forest University Health Sciences
Treatments:
Bevacizumab
Nintedanib