Overview

BEP Study Phase I (Bevacizumab, Everolimus, Panitumumab)

Status:
Completed
Trial end date:
2014-09-01
Target enrollment:
Participant gender:
Summary
Targeting molecular pathways of tumor growth has become a major focus of anti-cancer treatments. This study aims to investigate the toxicity, pharmacokinetics, and preliminary efficacy of the triplet combination of bevacizumab, RAD001, and panitumumab in patients with refractory solid tumors. This open-labeled, non-randomized phase I trial of bevacizumab, everolimus and panitumumab is designed to assess the safety, tolerability and efficacy of this combination in adult patients with advanced solid tumors.
Phase:
Phase 1
Details
Lead Sponsor:
Herbert Hurwitz, MD
Collaborators:
Amgen
Genentech, Inc.
Novartis
Treatments:
Antibodies, Monoclonal
Bevacizumab
Everolimus
Panitumumab
Sirolimus