Primary Objective:
- To determine the 8 week progression-free survival rate (i.e. disease control rate) in
patients with advanced non-small cell lung cancer (NSCLC) who have failed at least one
prior chemotherapy regimen.
Secondary Objective:
The secondary objectives of this study will be to:
- Determine the overall response rate
- Determine the overall survival
- Determine the time to disease progression
- Assess the safety/toxicity of the study treatment
- Assess biomarker modulation in the tumor tissue and serum samples from the treatment.
- Assess plasma and intra-tumor concentrations of study treatment