B181 Metobes-III: Weight Loss Maintenance of a New Bioactive Compound (Metobes-Long)
Status:
Completed
Trial end date:
2005-04-01
Target enrollment:
Participant gender:
Summary
To investigate the 5-hour acute effect on energy expenditure, substrate oxidation and ad
libitum food intake after intake of the Metobes-compound (green tea extract, capsaicin,
tyrosine, caffeine). Furthermore, to investigate if the effect of the Metobes-compound can be
inhibited by blocking the β-adrenergic receptors.
The effect of the Metobes-compound will be investigated by:
1. 5-hour energy expenditure and respiratory quotient (ventilated hood).
2. 5-h change in blood pressure and heart rate
3. 5-h change in sympathetic/parasympathetic ratio.
4. Ad libitum energy intake.
5. Self-reported postprandiel appetite sensations (VAS).