B-Lymphocyte Immunotherapy in Islet Transplantation
Status:
Terminated
Trial end date:
2011-09-01
Target enrollment:
Participant gender:
Summary
Type 1 diabetes is an autoimmune disease in which the insulin-producing pancreatic beta cells
are destroyed, resulting in poor blood sugar control. The purpose of this study is to
determine the safety and effectiveness of islet transplantation, combined with the
immunosuppressive medications and medications to support islet survival for treating type 1
diabetes in individuals experiencing hypoglycemia unawareness and severe hypoglycemic
episodes.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborator:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)