Azithromycin Reduction to Reach Elimination of Trachoma

• Status: Recruiting
• Trial end date: 2027-01-31
• Target enrollment: 0
• Participant gender: All

Summary

The investigators propose a randomized controlled trial of discontinuation versus continuation of annual mass azithromycin distribution in hypoendemic communities of Maradi, Niger. The investigators will randomize communities with up to 20% Trachomatous Inflammation

• Follicular (TF) prevalence following at least 5 years of mass azithromycin distribution to discontinuation or continuation of 3 additional years of annual mass azithromycin distribution.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of California, San Francisco
• Collaborators: Le Programme National de Santé Oculaire (PNSO); Programme National de Santé Oculaire (PNSO)
• Treatments: Azithromycin

Criteria

Inclusion Criteria:

• Provision of appropriate informed consent

• Stated willingness to comply with all study procedures

• Live in one of the 80 communities with up to 20% prevalence of TF selected for the trial

Exclusion Criteria:

• Does not consent to participation

• Unwilling to comply with all study procedures

• Does not live in one of the 80 communities with up to 20% prevalence of TF selected for the trial