Azelaic Acid Versus Hydroquinone in Melasma

• Status: Unknown status
• Trial end date: 2010-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the safety and effectiveness of Azelaic Acid Gel to Hydroquinone Cream in the treatment of melasma.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Callender Center for Clinical Research
• Treatments: Azelaic acid; Hydroquinone

Criteria

Inclusion Criteria:

• must have stable moderate-severe epidermal or mixed melasma involving the face

• all races

• males and females

• persons taking birth control medication, hormone replacement therapy or any other hormone altering medication may participate only if they have not started or stopped the medication within the last 3 months

Exclusion Criteria:

• if the person has only dermal melasma

• pregnancy, breastfeeding, a positive pregnancy test in the office or plans to become pregnant

• a known allergy or sensitivity ot azelaic acid or hydroquinone

• the use of photosensitizing medications (ex. tetracycline) within 3 months of the study.

• starting or stopping hormonal medication within 3 months

• chemical peels, microdermabrasion, or laser treatment within 6 months

• worsening or improving melasma