Azathioprine in the Prevention of Ileal Crohn's Disease Postoperative Recurrence.
Status:
Terminated
Trial end date:
2015-05-01
Target enrollment:
Participant gender:
Summary
The objective of this study is to evaluate if in the prevention of postoperative recurrence
of ileal Crohn's disease immediate initiation of azathioprine postoperatively is superior to
delayed (6- 12 mths.) introduction of azathioprine upon disease recurrence assessed by
endoscopic criteria. The primary endpoint, disease recurrence, encompasses symptomatic and
surgical recurrence as well as severe endoscopic lesions at the final, 2 year, assessment.
Phase:
Phase 2
Details
Lead Sponsor:
Universitaire Ziekenhuizen Leuven
Collaborator:
International organization for the study of inflammatory bowel disease (IOIBD)