Overview

Azacitidine in Combination With Venetoclax Treatment for MRD Positive Post Allo-HSCT AML/MDS Patients

Status:
Recruiting
Trial end date:
2026-03-19
Target enrollment:
Participant gender:
Summary
In patients with MRD-positive patients after AML/MDS allogeneic hematopoietic stem cell transplantation, azacytidine combined with venetoclax may be effective in eliminating micro residual diseases, reducing the risk of relapse, and ultimately improving long-term survival.The primary purpose of this study was to explore an effective protocol to reduce the risk of relapse in patients with MRD positive after allogeneic hematopoietic stem cell transplantation for AML/MDS.
Phase:
Phase 2
Details
Lead Sponsor:
First Affiliated Hospital of Zhejiang University
Collaborators:
First Affiliated Hospital of Wenzhou Medical University
Jinhua Central Hospital
Ningbo No. 1 Hospital
Second Affiliated Hospital, School of Medicine, Zhejiang University
Sir Run Run Shaw Hospital
Taizhou Hospital
The First Affiliated Hospital of Zhejiang Chinese Medical University
Union hospital of Fujian Medical University
Xiangya Hospital of Central South University
Yinzhou Hospital Affiliated to Medical School of Ningbo University
Zhejiang Provincial People's Hospital
Treatments:
Azacitidine
Venetoclax