This is a 2 part study. The goal of the first part of this clinical research study is to find
the highest tolerable dose of azacitidine that can be given with a TKI that you are already
taking (such as Gleevec, Sprycel, or Tasigna). The safety of this drug will also be studied.
The goal of the second part is to see if this combination may improve your response to the
TKI you are already taking.
Azacitidine is designed to change genes that are thought to cause leukemia. By changing these
genes, the drug may help to stop them from causing the disease to grow.