Axillary Reverse Mapping Using Near-infrared Imaging in Invasive Breast Cancer: Predictors of Nodal Positivity
Status:
Unknown status
Trial end date:
2019-07-01
Target enrollment:
Participant gender:
Summary
The initial standard treatment of breast cancer is surgery. Tumor involvement of lymph nodes
is of paramount importance in the subsequent management of this cancer and surgery of
invasive breast cancer involves axillary lymph node dissection (ALND). To preserve arm
lymphatic drainage during ALND and avoid the risk of arm lymphedema, mapping the lymphatic
drainage by axillary reverse mapping (ARM) has been developed. But oncological safety is
uncertain.
The ARM procedure presented here uses indocyanine green (ICG) and fluorescence detection of
draining lymphatics. The project aims to train surgeons to the technique and to identify
predictive factors for metastatic ARM nodes in invasive BC using tumor and axillary
pathological parameters to better select patients who would not require removal of the ARM
node in the future