Avoiding Risks of Thrombosis and Bleeding in Surgery (ARTS) Trial
Status:
RECRUITING
Trial end date:
2028-12-31
Target enrollment:
Participant gender:
Summary
Avoiding Risks of Thrombosis and bleeding in Surgery (ARTS) trial is a pragmatic, international, multicenter, randomized controlled open label trial comparing a direct oral anticoagulant (DOAC) - oral factor Xa inhibitor apixaban - to no anticoagulant among 5,436 patients undergoing abdominal or pelvic surgery at sufficiently similar (and not high) risk of venous thromboembolism (VTE) and bleeding that the net impact - benefit or harm - of thromboprophylaxis remains in doubt.
Phase:
PHASE4
Details
Lead Sponsor:
Clinical Urology and Epidemiology Working Group
Collaborators:
Albany Medical College Helsinki University Central Hospital North Karelia Central Hospital Oulu University Hospital PaijatHame Central Hospital Population Health Research Institute Tabriz University of Medical Sciences Tampere University Hospital Turku University Hospital University College, London University of Helsinki