Autonomous Nervous System Regulated Paediatric Anaesthesia With Dexmedetomidine or Placebo
Status:
Not yet recruiting
Trial end date:
2023-12-31
Target enrollment:
Participant gender:
Summary
The goal of this randomized, double blinded study is to examine in children whether
postoperative agitation can be reduced.
The main question it aims to answer is Will optimized, monitor guided analgesic treatment and
dexmedetomidine reduce postoperative agitation Participants will receive a standard
anaesthesia regimen and on top of that, a titrable remifentanil infusion guided via Mdoloris
Anastasia nociception index (ANI) monitor will be added. Additionally, the patients will
receive either bolus placebo or bolus dexmedetomidine. The postoperative agitation measured
via the Richmond agitation and sedation scale (RASS) score, will be compared. Secondary
outcome measures including carbon dioxide trends will be made.