Overview

Autologous and Allogenic Transplantation With Campath-1H for T-Cell Lymphoma

Status:
Terminated
Trial end date:
2009-11-01
Target enrollment:
Participant gender:
Summary
Primary Objectives: 1. To evaluate the role of autologous and allogenic stem cell transplantation with Campath-1H for patients with peripheral T-cell lymphoma (PTCL). 2. To examine the impact of in-vivo purging with Campath -1H pre-autologous stem transplantation for patients with PTCL. 3. To evaluate the impact of soluble CD52 upon in-vivo purging with Campath-1H. 4. To evaluate the role of Campath -1H in the treatment minimal residual disease after autologous transplantation for PTCL.
Phase:
Phase 2
Details
Lead Sponsor:
M.D. Anderson Cancer Center
Collaborator:
Bayer
Treatments:
Alemtuzumab
Carmustine
Cyclophosphamide
Cytarabine
Etoposide
Etoposide phosphate
Fludarabine
Fludarabine phosphate
Lenograstim
Melphalan
Molgramostim
Sargramostim
Vidarabine