Autologous Serum Efficacy Study in Patients With Severe Dry Eye

• Status: Completed
• Trial end date: 2008-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the reduction in symptomatology of patients with severe dry eye treated with autologous serum and conventional artificial tears.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Chile

Criteria

Inclusion Criteria:

• Age > 18 years

• Severe Dry Eye, as defined by a OSDI score > or = 40

Plus:

• Tear Break Up Time (TBUT) < 5 seconds

• Cornea-conjunctival epithelial defects measured by Fluorescein staining and evaluation using the Oxford score.

Exclusion Criteria:

• No dry eye associated ocular disease

• Unable to comply protocol

• Severe anemia

• Previous use of autologous serum

• Concomitant use of other topical ocular drug

• Hypersensibility to any proposed interventions