Overview

Autologous ROR1R-CAR-T Cells for Chronic Lymphocytic Leukemia (CLL)

Status:
Withdrawn
Trial end date:
2017-06-01
Target enrollment:
Participant gender:
Summary
Gene transfer is a process in which the DNA (genetic material) of certain cells is changed. In this study, gene transfer will be performed on a type of white blood cell (called T cells) to recognize leukemia cells in the same person the T cells were collected from. The goal of this clinical research study is to learn if it is safe to give these genetically-changed T cells back to patients with CLL/SLL. Researchers also want to learn if these cells can help to attack CLL/SLL cells.
Phase:
Phase 1
Details
Lead Sponsor:
M.D. Anderson Cancer Center
Collaborator:
CLL Global Research Foundation Alliance
Treatments:
Bendamustine Hydrochloride
Cyclophosphamide
Fludarabine
Fludarabine phosphate
Rituximab
Vidarabine