Overview

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors

Status:
RECRUITING
Trial end date:
2029-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to test the manufacturing feasibility and safety of intravenous (IV) administration of B7-H3CART in children and young adult subjects with relapsed and/or refractory solid tumors expressing B7-H3 target using a standard 3+3 dose escalation design.
Phase:
PHASE1
Details
Lead Sponsor:
Crystal Mackall, MD