Autologous Adipose-Derived Stromal Vascular Fraction Cells for Osteoarthritis Treatment
Status:
Completed
Trial end date:
2019-09-01
Target enrollment:
Participant gender:
Summary
Adipose-derived stromal vascular fraction cells (SVFs) include regenerative cell populations
(hematopoietic cells, pericytes, endothelial cells and progenitors, stromal/stem cells) and
thus are potentially important as new therapeutic tools for the repair and regeneration of
acute and chronically damaged tissues.
The general objective of this study is to evaluate safety and clinical efficacy of a single
intra-articular injection of freshly isolated auto-SVFs for the treatment of patients with
knee osteoarthritis (OA). This study uses autologous adipose-derived SVFs, as therapeutic
agent and intra-articular administration, as a mode of delivery. Expected clinical effects: a
treatment reduces pain, increases function and reduces stiffness in the knees of
osteoarthritic subjects.