Augmented Interoceptive Exposure Training in Anorexia Nervosa
Status:
Active, not recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
The researchers propose to utilize a pharmacological approach involving infusions of the
sympathomimetic agent isoproterenol to repeatedly trigger cardiorespiratory sensations and
anxiety during meal anticipation, to facilitate the development of tolerance or a reduction
of the anxiety/fear response in individuals with anorexia nervosa. The investigators aim to
conduct a proof of principle study to assess for evidence of initial efficacy of this new
treatment approach. As a comparator condition, the researchers propose using repeated
administration of saline infusions.