Atypical Antipsychotic Treatment Effect On Brain Function In Schizophrenia Measured By FMRI
Status:
Completed
Trial end date:
2007-12-01
Target enrollment:
Participant gender:
Summary
The general aim is to compare the effects of typical and atypical antipsychotic medication on
brain structure and function. A parallel group treatment trial will be utilized to compare
the effects of the typical antipsychotic thiothixene versus the atypical antipsychotics
risperidone (RIS) and olanzapine (OLZ) on brain structure and function in schizophrenia in an
effort to determine the neuroanatomic basis for cognitive pathology in schizophrenia and its
amelioration by atypical antipsychotic drugs.