Atrovent in Exercise Induced Laryngeal Obstruction (EILO)

• Status: Completed
• Trial end date: 2020-10-31
• Target enrollment: 0
• Participant gender: All

Summary

Exercise Induced Laryngeal Obstruction (EILO) is a condition not uncommon in otherwise healthy young people. EILO is caused by posteromedial collapse of supraglottic structures or medialization of the vocal folds, or both, during high intensity exercise. There are currently no treatments available that is properly evidence based. However, case reports suggest a possible effect from the "asthma drug" Ipratropium Bromide (Atrovent®). The current project is an open label pilot study, aiming to test if Atrovent can influence the occurence of EILO, either postponing the onset during exercise or fully prevent the condition to occur.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Haukeland University Hospital
• Treatments: Bromides; Ipratropium

Criteria

Inclusion Criteria: Exercise Induced Inspiratory Symptoms and a CLE score Equal to or larger than three Exclusion Criteria: Participants should be free from co-morbidities other than stable and weel treated asthma. Pregnancy