Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb Surgeries

• Status: Unknown status
• Trial end date: 2018-09-01
• Target enrollment: 0
• Participant gender: All

Summary

A study to compare between intravenous atropine and glycopyrrolate in preventing spinal anesthesia induced hypotension in patients undergoing major lower limb orthopedic surgeries. Hypotension is the most common complication in spinal anesthesia that can be life threatening. If this can be prevented patients comfort can be increased and satisfaction as well.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: B.P. Koirala Institute of Health Sciences
• Treatments: Atropine; Glycopyrrolate

Criteria

Inclusion Criteria:

• ASA PS I and II,

• age 16 to 65,

• undergoing lower limb major orthopedic surgery,

• willing to participate

Exclusion Criteria:

• Contra indication to spinal anesthesia,

• patient refusal,

• ASA PS >III,

• cardiac diseases,

• hypertension >160/ 100,

• arrhythmias,

• Acute coronary syndrome,

• patients taking beta-blockers,

• hepatic and pulmonary diseases