Overview

Atazanavir or Lopinavir in HIV Post-exposure Prophylaxis

Status:
Completed
Trial end date:
2009-08-01
Target enrollment:
0
Participant gender:
All
Summary
The study compares the adherence of 240 HIV-negative subjects randomly assigned to 2 different antiretroviral therapies for 28 days after accidental exposure to HIV.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Hospital Clinic of Barcelona
Treatments:
Atazanavir Sulfate
Lamivudine
Lamivudine, zidovudine drug combination
Lopinavir
Zidovudine
Criteria
Inclusion Criteria:

- Age > 18

- HIV exposure requiring prophylaxis under current guidelines

Exclusion Criteria:

- Pregnancy

- Suspected drug resistance in source case

- Contraindications to the study drugs