Asymptomatic Carotid Artery Plaque Study (ACAPS)

• Status: Completed
• Trial end date: 1998-08-01
• Target enrollment: 0
• Participant gender: All

Summary

To determine whether warfarin or lovastatin alone or in combination retarded the progression of atherosclerotic plaques in the carotid arteries of high risk individuals with asymptomatic carotid stenosis. Also, to determine if a full scale trial was feasible.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
• Treatments: Aspirin; Dihydromevinolin; L 647318; Lovastatin

Criteria

Men and women with early carotid atherosclerosis and moderately elevated LDL cholesterol between the 60th and 90th percentiles.