The investigators propose to study the patterns of metabolite changes in subjects with asthma
to determine if there is a predictable pattern prior to, and post, clinical exacerbation.
Hypothesis: 1. Metabolite profiles will change prior to detection of a clinical exacerbation
in subjects with asthma.
2. There will be a measurable temporal delay before metabolite profiles return to baseline
following anti-inflammatory therapy of an exacerbation of asthma.