Asthma Biomarkers for Predicting Response to Therapy
Status:
Unknown status
Trial end date:
2016-07-01
Target enrollment:
Participant gender:
Summary
Novel asthma biomarkers to predict the response to inhaled corticosteroid Brief description:
This will be a single center study of asthmatic subjects and healthy controls which will
investigate mechanisms underlying different response to inhaled corticosteroid, the mainstay
of asthma therapy. Only about half of the asthmatic patients have improved lung function
after treatment of inhaled corticosteroid. The investigators hypothesize that there are
biomarkers such as epithelial cytokines (IL-25, IL-33, TSLP) in airway tissues or plasma of
asthmatic patients which could predict the response of asthmatic patients to inhaled
corticosteroid. Finding novel asthma biomarker will help the clinicians to choose the optimal
treatment for individual asthmatic patient.