Association of Cathelicidin and Vitamin D Levels With the Category and Course of COPD

• Status: Completed
• Trial end date: 2021-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Recruitment of patients with COPD. Assessment of clinical status, determination of vitamin D and cathelicidin levels. In the group with vitamin D deficiency, patients receive cholecalciferol (vitamin D) daily for 3 months. After 3 months, the clinical status was assessed again, the level of vitamin D and cathelicidin was determined. When vitamin D levels normalize, cholecalciferol replacement therapy is discontinued for 3 months. After that, a control inspection and laboratory tests are performed.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Karaganda Medical University
• Treatments: Cholecalciferol

Criteria

Inclusion Criteria:

• Clinically confirmed chronic obstructive pulmonary disease

Exclusion Criteria:

• age under 18

• pregnancy

• mental disorders

• cancer

• terminal renal and hepatic insufficiency