Overview

Assessment of the Effect of Naltrexone on Lofexidine Single Dose Pharmacokinetics in Healthy Subjects

Status:
Completed
Trial end date:
2015-06-01
Target enrollment:
Participant gender:
Summary
A Phase 1, open-label, single-arm study with two single doses of lofexidine and multiple doses of naltrexone in healthy adult subjects to determine the effect of naltrexone on the single dose pharmacokinetics of the oral lofexidine formulation.
Phase:
Phase 1
Details
Lead Sponsor:
US WorldMeds LLC
Collaborator:
National Institute on Drug Abuse (NIDA)
Treatments:
Clonidine
Lofexidine
Naltrexone