Assessment of the Effect of Gluten Free Toothpaste on the Ulcerative Events in Children With Celiac Disease
Status:
Completed
Trial end date:
2020-01-21
Target enrollment:
Participant gender:
Summary
Celiac disease (CD) is the most common genetically based food intolerance in the world, with
a prevalence among approximately 1% of the general population (Guandalini & Assiri, 2014). CD
is a frequent disorder among Egyptian children, both in the general population and in at-risk
groups(Abu-Zekry et al., 2008). It is estimated that the incidence of CD is 3 to13 cases
per1000, with a higher prevalence among first-degree relatives of patients with CD.Lifelong
adherence to a strict gluten free diet (GFD) remains the only available treatment for
patients with CD and typically results in a complete return to health. Nevertheless, gluten
is not found only in diet, Gluten is commonly used as a binder in products like medication,
cosmetics, oral and skin care, and even children's toys. Gluten is found also in toothpastes
and other oral health products and it can be swallowed by mistake and initiate immune
response(Anon, n.d.). Unfortunately, there is no gluten free toothpaste available in the
Egyptian market and it is very expensive if we bought it from Europe or USA. The tube will
cost nearly 10 dolars .As a result, the production and availability of gluten free toothpaste
in Egypt has become mandatory.