Assessment of Voriconazole Penetration Into the Brain by Fluorine-Magnetic Resonance Spectroscopy

• Status: Completed
• Trial end date: 2005-05-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of this study is to determine the amount of voriconazole in the brain by fluorine-magnetic resonance spectroscopy (MRS) and to compare brain levels to plasma levels.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Pfizer
• Collaborator: Mclean Hospital
• Treatments: Voriconazole

Criteria

Inclusion Criteria:

• Healthy male volunteers 18-55 years of age

Exclusion Criteria:

• Subjects with any condition affecting drug absorption

• Subjects with a positive urine drug screen