Assessment of Ventilation-perfusion Abnormalities in Patients With Stable Smoking-related Airways Disease
Status:
Terminated
Trial end date:
2008-02-01
Target enrollment:
Participant gender:
Summary
Subjects undergo history, examination, lung function assessment after informed consent has
been obtained. All subjects will undergo ventilation-perfusion scans. If there first scan is
normal they will undergo a second and final scan four weeks later. If abnormal they will
undergo two further scans with either nebulized bronchodilator or nebulized saline prior to
their second and third scans. Each time they will have repeat lung function tests prior to
scanning. We will examine the regional changes in ventilation and perfusion and there
relationship to lung function.