Assessment of Peripheral GABA Receptors for Local Pain Relief
Status:
Unknown status
Trial end date:
2019-12-01
Target enrollment:
Participant gender:
Summary
The effect of peripheral GABAA receptor activation on pain and sensitivity in healthy human
subjects has never been investigated. However, as earlier studies suggest that activation of
peripheral GABAA receptors is anti-nociceptive in rats, it is important to determine if these
findings can be translated into human subjects to determine if peripheral GABAA receptors are
a viable target for future analgesic drug development.